Nineteen of the Russian's 21 titles have been achieved on hard courts
A revitalized the Russian player won his initial championship for over two years with victory over Corentin Moutet in the competition final.
Medvedev, a ex- world number one, has endured a difficult period, achieving just one win at the big events and experiencing a meltdown at the US Open.
His unpredictability on the tennis tour - and issues with his serving in specific - resulted in him dropping out of the elite rankings and ultimately splitting with long-time coach Gilles Cervara.
Presently collaborating with Thomas Johansson and Rohan Goetzke, the tennis star has steadily improved in the past month - climaxing in a closely contested three-set triumph over Frenchman Moutet.
It is the player's maiden championship after the Italian tournament and first on a hard court after that period of the previous year.
Victory also signifies he has secured twenty-one titles at twenty-one different events.
"This marks the first occasion I am participating in a event with my two daughters at once, so to win a championship is really nice," commented tennis professional Medvedev.
"This victory is in tribute of my child Victoria, because the initial championship I got when my first daughter her name was born was for her."
The athlete, the former major winner, had lost his previous six championship matches, featuring in Halle in the past months.
His defensive play style and regular emotional displays on the playing surface had prompted commentators to wonder if his ability to play at the highest level was finished.
Yet the 29-year-old has made changes in the past month, striving to come to the net and compete aggressively, backed up by an improved serving game.
He recovered from a deficit in the initial set against the challenging opponent, securing 4 of the concluding five exchanges to gain the advantage.
The competitors exchanged service breaks in the second set before Moutet, striving for his initial tour title, took control to create a final set.
He saved four initial opportunities in a tight deciding set before the Russian won the break to fifteen to serve for the match.
Suitably, Medvedev earned victory with a rally at the front of the court, with the Frenchman unable to handle a shot after a lengthy match.